Finalist
DoctorDean
What I built.
sciencedev toolsagents
Dean Sherry
AI lab hackathons, 2025 to now
What got built, and what won.
Every submission from hackathons run by Anthropic, OpenAI, Google, Meta and the other big labs, with the winners marked and the code linked.
- projects
- 31,980
- hackathons
- 93
- award winners
- 585
- inferred from GitHub
- 433
Finalist
Jaymin
I used Claude to train a protein language model that can generate an extremophilic version of any enzyme, maintaining its function, while allowing it to survive extreme temperatures, pH, salinity, etc.
science
Jaymin Patel
Finalist
Faith Ogundimu
Diffuse midline glioma is a paediatric brainstem cancer that is almost uniformly fatal: about ninety percent of children die within two years, and the first systemic drug, approved in 2025, does not cure.
healthscience
Faith Ogundimu
Finalist
About Trialign
About Trialign is a patient-facing clinical trial matcher for oncology.
health
Neil Wang, Jules Park
Finalist
Hippocampus AI
Hippocampus AI is the memory and reasoning engine for scientific discovery.
scienceagents
Finalist
Tina Lasisi
Many primates are sexually dichromatic — males and females are different colors.
science
Tina Lasisi
Finalist
Springbuilt
Hi!
healthscience
Shereen Lee
Motif
Motif is a molecular-biology workbench that runs inside Claude Science as a plugin.
sciencedev tools
Jacob Vogan
PerturbGate
PerturbGate is an open-data, reproducible pipeline that turns a genome-scale primary human CD4 T-cell Perturb-seq screen into evidence-gated mechanism hypotheses — not another ranking of hits.
sciencehealth
Margarita Soloshenko
SpatialScribe
SpatialScribe is a self-serve copilot for imaging-based spatial transcriptomics (Xenium, CosMx, MERSCOPE, and whole-transcriptome Atera).
sciencehealth
Paul Gueguen
Vellum
Vellum is a glass-box agentic ICD-10 coder.
healthfinance
Fareed Khan
Verastar
Verastar is a morning literature harness built by and for a busy vascular surgeon who can't read the hundreds of papers published in her field each month, yet can't afford to miss them.
healthscience
Marissa Famularo
SecondLook
SecondLook is a trust layer for an AI basal cell carcinoma detector, built for a dermatopathologist, Mohs surgeon, or dermatologist reading skin-pathology slides under real clinic load, where long days and fatigue nudge
healthvision
Edward Yi
Sam's team
built two open-source tools that solve problems I kept seeing in computational biology.
sciencedev tools
Samuel Bharti
CuraVar
CuraVar is a "show your work" assistant for classifying genetic variants.
healthscience
Husnain Arif
CBMR Multimodal
**What we investigated.** ML leaderboards present ranked models with narrow error bars, which reads as evidence of predictive strength.
scienceagents
Dewei Hu
G-perturb
G-perturb re-ranks drug targets from a genome-scale CD4+ T-cell Perturb-seq screen by whether each effect is dependable, not just by how large it is.
sciencehealth
Che Cheng
NOTE
NOTE: Please read the manuscript in github.
healthscience
Jaron Mohammed
Stanza
I built Stanza to chase a frustrating question: when a resistance mutation kills a cancer drug, can you get to a redesigned molecule in minutes instead of years?
healthscience
Ayush Kumar
Sabih
We mapped the causal control architecture of a human immune cell and used it to nominate druggable, disease-relevant targets.
sciencehealth
Syed Sabih ur Rehman
PaedScale
PaedScale — a starting pediatric dose from adult pharmacokinetics, with a cited rationale Most drugs are never trialed in children, so when a kid needs one that has no pediatric label, clinicians extrapolate the dose by
healthagents
Dhruvik Pandya
CisFalcon
AI now designs synthetic enhancers meant to switch a gene on in one cell type and stay silent everywhere else.
sciencehealth
Ubaidullah Shuaib
Cruciblees
Science has always started with people with a question, an idea, and the work to turn it into a finding.
scienceagents
Lucas Stoffl, Abhishek Thanki
Genome Therapy
Sequence-to-expression "oracles" (Enformer, Borzoi, AlphaGenome, Evo2) and the generative-DNA designers built on them all aim to predict how cis-regulatory DNA sets a gene's expression.
sciencehealth
Qihao Duan
Oocytezero
OocyteZero asks a concrete question behind a disease that affects up to 1 in 8 women: can today's DNA-reading AI models name the single causal base at an unsolved PMOS (polycystic ovary syndrome) genetic locus?
healthscience
Jose Contreras
Nick Lamb
When two well-run papers disagree, it is rarely because one of them is wrong.
sciencedev tools
Nick Lamb
CREative
To understand how Alzheimer’s disease reshapes the brain’s regulatory landscape cell type by cell type, I used Claude Science to analyze Droplet Paired-Tag data from 10 donors across the hippocampus and cerebellum.
healthscience
Protocol To Data
protocol-to-data turns a clinical trial protocol into a validated, analyzable synthetic SDTM dataset in one Claude-driven agentic loop.
healthdev tools
Chetan Tamballa
Meow
Immune checkpoint blockade (ICB) reactivates T cells to kill tumors and has transformed cancer treatment, but many patients don't respond.
healthscience
Shanshan Yin
Anuj Dev Singh
I tested a specific, high-stakes question for disease genetics: can today's best sequence-to-function deep-learning models (AlphaGenome, Borzoi, and the DeepSEA/Basset lineage) predict the DIRECTION — up or down — of a n
sciencehealth
Anuj dev Singh
Claudician
I built Clinical Digital Twin, an open-source R system (Shiny/plotly dashboard, plumber API, SQLite, and a Telegram bot powered by Claude) that gives clinicians in elder-care institutions a personalized, interpretable mo
healthagents
Daniel Gallardo
OPUS-ET-AGENT
OPUS-ET-AGENT: agent-conducted cryo-electron tomography Cryo-electron tomography (cryo-ET) is the only technique that resolves macromolecules at near-molecular detail inside intact cells.
scienceagents
Zhenwei Luo
Panoscope
Panoscope is a grounded interpretation layer over jazzPanda's spatial-transcriptomics output.
healthscience
Xinyi Jin
Everyone
Everyone builds bigger models to predict what a gene knockdown does.
science
Lukas Weidener
Wen Group
Cell-Type-Resolved Chromatin Effects of AD/PD Variants: DNA Language Model vs.
science
DeepPro-v2
DeepPro-v2 is a multi-view, multi-backbone deep learning model for prokaryotic promoter prediction across 23 species.
science
Johnson V
Evolution Arena
Evolution Arena is an interactive 3D WebGL survival game that turns evolutionary biology into something you can experience rather than simply read about.
education
JJ Ben-Joseph
Odola Labs
I created a workbench where you can name a protein and specify an objective in simple terms, and the agent will then manage the entire campaign.
scienceagents
Chinmay Pala
Kilian Maire
Repertoire2Structure (R2S) is a multi agent pipeline, orchestrated by Claude, that turns a raw 10x single cell TCR repertoire into QC'd predicted TCR to peptide MHC structures for its top clonotypes, with honest specific
scienceagents
Kilian Maire
Molaro
Molaro is a next-generation molecular dynamics environment built as a VS Code extension.
sciencedev tools
Dominic Fico
Markus Sommer
Determining whether a cancer patient responds to immunotherapy, detecting contamination in food and water, measuring mitochondrial membrane potential: scientists depend on flow cytometry.
healthscience
Markus Sommer
Myomatlas
Myomatlas is an open, image-based decision-support tool for abnormal uterine bleeding, one of the most common and most under-addressed problems in women's health.
healthvisionagents
GeneGround
GeneGround is a claim-level grounding layer for AI-generated omics interpretations.
scienceagents
Rhea Zhou
Clonal Compass
Clonal Compass is a single-cell immune-repertoire co-pilot for paired scRNA-seq + TCR-seq data.
science
Trish Whetzel
Litmus
Litmus reads a scientific paper and tells you how much to trust it before you build on it.
science
Aarush Agarwal
David Fraile Navarro
GLP-1 drugs like Ozempic are among the world's most prescribed — and in 2023 regulators opened suicide investigations after adverse-event databases lit up, even though the randomised trials showed no such risk.
healthscience
David Fraile Navarro
Cellarium
Cellarium is a tool for asking questions of the whole-cell model of E.
scienceagents
Evangelos-Marios Nikolados, Filippo Menolascina
Enactome
Enactome is a connectome-constrained simulation platform that loads the BANC Drosophila connectome (composed of 158,262 neurons, 3,990,039 synapses), signs each synapse by its presynaptic transmitter, and evaluates circu
science
Mehmet Kerem Turkcan
Clinibrium
Clinibrium is a clinical decision-support co-pilot for the otoneurology clinic, developed with a subspecialist otolaryngologist.
healthagents
Manuel Pena Zuniga
Litmuz
Litmuz is a claim-level verification layer for life-sciences research agents.
scienceagents
Jophin George Joseph
I built Mechanome, a physics-first inference engine that recovers mechanical forces in cells from protein structure and microscopy.
science
Jophin George Joseph
Provenance Gate (solo team)
I investigated a failure mode of agentic science: as an agent forks approaches, revises an upstream step, and re-runs, a final result can quietly come to rest on stale or version-conflicting inputs.
sciencedev tools
Sergey Aganezov
Seqcolyte
Seqcolyte is an open-source, protocol-aware platform for sequencing quality control and root-cause diagnosis.
sciencedev tools
chilam p
The Weavers of Fate
Norn (https://norn-five.vercel.app/) is a variant-interpretation copilot for clinical geneticists.
healthscience
Vignesh Nagarajan
futurelarry
## Project description — agent-eln ### What I built **agent-eln** is an AI-native lab operating system: a single git repo that unifies an Electronic Lab Notebook (ELN), a Laboratory Information Management System (LIMS),
scienceproductivity
NeuroVas Copilot
NeuroVas Copilot: An Interrogable 3D Aneurysm Reasoning Tool What we built Unruptured brain aneurysms present a difficult decision: treat now with clipping, coiling, or a flow diverter, or monitor and wait.
healthvision
Garvit Jain, Ronuk Gadamsetty
Sourced
Sourced is a provenance-first medication safety review tool for clinicians and pharmacists.
healthsecurity
Railly Hugo
Persona
Persona is a persistent, always-on synthetic researcher for the biomedical literature.
scienceagents
Aryan Singh
NUDGE
NUDGE — an "honesty engine" for AI-driven science.
science
Nicholas Roy
Noozra
Two open-source tools, built with Claude, that catch expensive biology failures early — on public data, as decision-support (never a diagnosis).
scienceagents