Motif
Motif is a molecular-biology workbench that runs inside Claude Science as a plugin.
Core trick
Every derived sequence record stores its parent ID and the transform that produced it, so any result can be traced back.
Description
Motif is a molecular-biology workbench that runs inside Claude Science as a plugin. Instead of answering sequence questions with prose, it turns a request into a real object you can inspect: annotated DNA, RNA, and protein records, circular and linear plasmid maps, restriction digests and gels, primer design and PCR, Gibson, Golden Gate, and GoldenBraid planning, multiple-sequence alignment, Sanger trace review, and typed analysis results. Every derived record keeps its parent and the transform that produced it, so results can be traced and checked. The bio functions are deterministic, so the same request gives the same answer.
The workbench is a single self-contained HTML artifact that runs locally in the browser. A narrow MCP connector mounts the interface inside Claude Science, with a saveable HTML fallback for hosts that do not mount MCP Apps. Nothing leaves the machine.
README excerpt
<p align="center"> <img src=".github/assets/motif-banner.png" alt="Motif — a molecular biology workbench." width="100%" /> </p> # Motif [Website](https://jvogan.github.io/motif-site/) · [Codex setup](docs/CODEX_QUICKSTART.md) · [Claude Science setup](docs/CLAUDE_SCIENCE_QUICKSTART.md) · [Capabilities](docs/CAPABILITIES.md) · [Examples](examples/README.md) · [Security](SECURITY.md) Motif is an AI-native molecular-biology workbench for exploring, editing, annotating, aligning, comparing, and sharing DNA, RNA, and protein records and analysis results. Its core is a self-contained HTML workspace that can run on its own or open through an AI host. The same Motif runtime supports sequence records, maps, annotations, alignments, cloning workflows, Sanger traces, provenance, checkpoints, and portable exports. ## Ways to use Motif | Experience | Best for | Start here | | --- | --- | --- | | Portable HTML workbench | Local inspection, editing, and sharing without a host integration | [Develop from source](#develop-from-source) | | Codex skills-only plugin | Creating portable workbenches directly from Codex | [Skills-only guide](docs/CODEX_SKILLS_ONLY.md) | | Codex local plugin | Opening interactive workbenches through the local MCP App | [Local plugin quickstart](docs/CODEX_QUICKSTART.md) | | Claude Science adapter | Opening Motif from a local Claude Science connector | [Claude Science quickstart](docs/CLAUDE_SCIENCE_QUICKSTART.md) | The Codex local plugin and Claude Science ad